David Oupický Selected Research

aziridine (ethyleneimine)

1/2018	Pulmonary delivery of polyplexes for combined PAI-1 gene silencing and CXCR4 inhibition to treat lung fibrosis.
2/2017	Combining Fluorination and Bioreducibility for Improved siRNA Polyplex Delivery.

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David Oupický Research Topics

Disease

41	Neoplasms (Cancer) 02/2023 - 03/2003
12	Neoplasm Metastasis (Metastasis) 08/2022 - 05/2014
9	Pancreatic Neoplasms (Pancreatic Cancer) 12/2022 - 01/2010
5	Breast Neoplasms (Breast Cancer) 08/2022 - 09/2010
4	Fibrosis (Cirrhosis) 03/2022 - 12/2017
4	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 09/2019
4	Hypoxia (Hypoxemia) 04/2019 - 01/2017
3	Colonic Neoplasms (Colon Cancer) 05/2022 - 01/2017
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022 - 01/2018
2	Ischemia 01/2022 - 09/2019
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2021 - 12/2018
2	Inflammation (Inflammations) 02/2021 - 12/2018
2	Cholangiocarcinoma 01/2018 - 03/2016
1	Liver Diseases (Liver Disease) 03/2022
1	Reperfusion Injury 01/2022
1	Adenocarcinoma 12/2021
1	Lung Diseases (Lung Disease) 10/2021
1	Colitis 02/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020
1	Leukemia 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019
1	Hemolysis 01/2017
1	Hyperthermia 09/2016
1	Melanoma (Melanoma, Malignant) 12/2014

Drug/Important Bio-Agent (IBA)

19	Small Interfering RNA (siRNA)IBA 02/2023 - 01/2010
12	Chemokine ReceptorsIBA 01/2022 - 05/2014
9	MicroRNAs (MicroRNA)IBA 03/2022 - 03/2016
7	Chloroquine (Aralen)FDA LinkGeneric 12/2022 - 03/2003
7	PolyaminesIBA 05/2022 - 09/2010
6	Nucleic AcidsIBA 01/2023 - 01/2010
5	plerixafor FDA Link 02/2023 - 07/2014
5	ProdrugsIBA 05/2022 - 06/2012
5	PolymersIBA 01/2022 - 12/2014
4	LipidsIBA 01/2023 - 03/2003
4	N(1),N(11)-diethylnorspermineIBA 05/2022 - 09/2010
4	Photosensitizing Agents (Photosensitizers)IBA 01/2020 - 09/2016
3	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2022 - 08/2017
3	Polo-Like Kinase 1IBA 05/2022 - 12/2021
3	LigandsIBA 02/2016 - 05/2014
2	Proteins (Proteins, Gene)FDA Link 01/2023 - 12/2017
2	RNA (Ribonucleic Acid)IBA 03/2022 - 01/2019
2	FluorocarbonsIBA 03/2022 - 01/2022
2	polycationsIBA 01/2022 - 02/2015
2	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 01/2018
2	ChitosanIBA 01/2022 - 12/2017
2	Therapeutic UsesIBA 12/2021 - 01/2020
2	Gemcitabine FDA Link 12/2021 - 01/2018
2	CholesterolIBA 12/2021 - 01/2020
2	Silicon Dioxide (Silica)FDA LinkGeneric 01/2020 - 01/2017
2	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2020 - 01/2017
2	ChemokinesIBA 01/2019 - 03/2016
2	EnzymesIBA 01/2018 - 01/2016
2	aziridine (ethyleneimine)IBA 01/2018 - 02/2017
2	Coloring Agents (Dyes)IBA 05/2017 - 09/2016
2	Drug CombinationsIBA 01/2017 - 09/2010
2	DNA (Deoxyribonucleic Acid)IBA 12/2014 - 01/2010
1	Tocopherols (Tocopherol)IBA 02/2023
1	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2022
1	Nerve Growth Factor (NGF)IBA 03/2022
1	EmulsionsIBA 03/2022
1	perflubron (L 1913)FDA Link 01/2022
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022
1	FluorineIBA 10/2021
1	EicosanoidsIBA 02/2021
1	Biomarkers (Surrogate Marker)IBA 02/2021
1	N-end cysteine peptide tumor-homing peptideIBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	cyclamIBA 12/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018
1	2-(dimethylamino)ethyl methacrylateIBA 01/2018
1	4-nitro-4'-aminodiphenyl sulfone (NADS)IBA 01/2018
1	Plasminogen Activator Inhibitor 1IBA 01/2018
1	AntagomirsIBA 01/2018
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2018
1	Biological FactorsIBA 01/2018
1	poly(ethylene glycol)- block- poly(2- methyl- 2- carboxylpropylene carbonate-graft-dodecanol)IBA 01/2018
1	salvianolic acid BIBA 12/2017
1	catechol (pyrocatechol)IBA 12/2017
1	Starch (Cornstarch)IBA 08/2017
1	homocamptothecinIBA 04/2017
1	Tirapazamine (SR 4233)IBA 01/2017
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2017
1	N-(1,4,8,11- tetraazacyclotetradecanyl- 1,4- phenylenebis(methylene))- 2- (aminomethyl)- pyridineIBA 01/2017
1	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2017
1	hydroxypropyl methacrylateIBA 03/2016
1	AminesIBA 03/2016
1	Chemokine CXCL12IBA 02/2016

Therapy/Procedure

23	Therapeutics 01/2023 - 01/2010
5	Drug Therapy (Chemotherapy) 12/2021 - 06/2008
3	Lasers (Laser) 01/2019 - 09/2016
2	Radiotherapy 01/2019 - 06/2008
2	Oral Administration 05/2017 - 09/2016
1	Electrocoagulation (Electrocautery) 01/2019
1	Cryosurgery 01/2019
1	Intravenous Injections 01/2018
1	Intravenous Administration 01/2018
1	Injections 01/2017
1	Photochemotherapy (Photodynamic Therapy) 01/2017
1	Photothermal Therapy 09/2016